IL-21 Protein, Rat Proteins and Enzymes and is anchored to the

and is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor

Once the T cell receptor binds its specific antigen Lck phosphorylates the cytoplasmic CD3 and ζ-chains of the TCR complex which initiates a cascade of phosphorylation eventually leading to activation of transcription factors like NFAT

Gly2250-Asn2450

OX40 also plays a crucial role in both Th1 and Th2 mediated reactions in vivo

IL-21 Protein, Rat Proteins and Enzymes and is anchored to theProduct Specification Species Rat Synonyms Interleukin 21, IL 21 Accession A3QPB9 Amino Acid Sequence His18 Ser146 Expression System E. coli Molecular Weight 15kDa Purity 95% by SDS PAGE&RP HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 400mM NaCl, pH8. 0 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.