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Insulin-degrading enzyme (IDE) is a key enzyme involved in the breakdown of insulin and has been implicated in the pathophysiology of both type 2 diabetes and Alzheimer's disease
with C-terminal 8*His QLTIESRPFNVAEGKEVLLLAHNLPQNTLGFNWYKGERVDAKRLIVAYVIETQQTTPGPAHSGRETVYSNASLLIQNVTQNDTGSYTLQVIKGDLVNEEATGRFWVYPELPKPYITSNNSNPVEDKDAVDFTCEPDIHSTTYLWWVNDQSLPVSPRLQLSNGNRTLTLLSVKRNDAGAYECEIQNPVSANLSDPVILNVLYGPDVPTISPSNSNYRPGENLNLSCHAASNPTAQYSWFVNGTFQQSTQELFIPNITVNNSGSYMCQAYNSATGLNRTTVMMITVSGGGGSHHHHHHHH Expression System HEK293 Molecular Weight 55-72kDa Purity >95% by SDS-PAGE Endotoxin <0
Because the chemical and biological characteristics of various subtypes are different
The proteins whose cDNA sequences have so far been identified are bovine and ovine PAG1
Alexa Fluor® 488 Rat Anti-Mouse CD45 Antibody (S-R477) Proteins and Enzymes Insulin-degrading enzyme (IDE) is aProduct Specification Host Rat Antigen Mouse CD45 Synonyms Receptor type tyrosine protein phosphatase C, Leukocyte common antigen (L CA), T200, PTPRC Location Cell membrane Accession P06800 Clone Number S R477 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0. 3% Proclin 300 Stability &